IndraLab

Statements

OTUB1 activates Hypoxia. 6 / 6
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"OTUB1 augments hypoxia signaling via its non-canonical ubiquitination inhibition of HIF-1alpha during hypoxia adaptation."
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"In this study, we found that OTUB1 augments hypoxia signaling independent of PHDs/VHL and FIH."
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"Furthermore, OTUB1 promotes hypoxia-induced glycolytic reprogramming for cellular metabolic adaptation."
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"This phenomenon provoked us to investigate the impact of OTUB1 on hypoxia signaling.In this study, we found that OTUB1 augments hypoxia signaling independent of PHDs/VHL and FIH."
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"OTUB1 augments hypoxia signaling."
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"Overexpressing OTUB1 augments hypoxia gene induction while knocking down OTUB1 has the opposite effect (Liu et al., 2022)."
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