IndraLab

Statements

MYSM1 activates cell population proliferation. 6 / 6
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"Survival and proliferation of melanoma cells is supported by MYSM1."
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"These findings indicated that MYSM1 promotes cell proliferation and colony formation and attenuates SA-beta-Gal activation to repress senescence ."
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"Mysm1 -/- mice had enhanced HSC proliferation that led to a large dysfunctional LSK population."
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"Knockdown of MYSM1 promoted cell proliferation and suppressed senescence of CRPC cells under condition of androgen ablation."
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"Meanwhile, MYSM1 knockout reduces the proliferation of osteoclast progenitor and the osteoclast resorption activity [130]."
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"In a separate study, Mysm1 -/- macrophages were confirmed to have elevated production of pro inflammatory cytokines in response to stimulation, as well as increased proliferation, increased apoptosis, and enhanced capacity to control melanoma tumor growth in vivo in mouse models [XREF_BIBR]."
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