IndraLab

Statements

USP22 increases the amount of adenosine 5'-(pentahydrogen tetraphosphate). 6 / 6
| 6
reach
"As shown in Figure XREF_FIG, USP22 activates AP4 expression during EMT induction."
28427243
reach
"In summary, USP22 induces EMT by activating AP4 transcription to enhance CRC cell migration and invasion."
28427243
reach
"USP22 induces EMT by activating AP4 transcription."
28427243
reach
"The key findings of the study are as follows : (i) USP22 enhances CRC cell migration and invasion by inducing EMT, (ii) USP22 directly increases AP4 transcription to induce EMT and promote CRC cell metastasis to the lungs in vivo, and (iii) USP22 and AP4 overexpression is related to CRC progression and liver metastasis and poor outcomes in CRC patients."
28427243
reach
"Moreover, USP22 up-regulation induces EMT by directly increasing AP4 transcription, resulting in CRC cell metastasis to the lungs in vivo."
28427243
reach
"USP22 up-regulation enhances CRC cell migration and invasion and EMT related marker and AP4 expression, but these effects are partly blocked by AP4 knockdown."
28427243