IndraLab

Statements

KCNB2 binds SNP. 3 / 3
| 3
sparser
"The top SNP associations were: for LV diastolic dimension, a SNP associated with SLIT2 gene; for LV systolic dimension, a SNP associated with KCNB2 gene; and for LV mass, and left atrial size, SNPs associated with FAM5C gene."
19945067
sparser
"Interestingly, a SNP × SNP epistasis analysis of the 66 replication SNPs in the Finnish case–control sample detected an interaction between KCNB2 SNP rs1431656 on chromosome 8q13.3 and CACNB2 SNP rs7076100 on chromosome 10p12.33 (point-wise P = 0.0000199), which remained significant after conservatively correcting for all 2145 possible interaction tests [i.e. treating the 66 replication SNPs as independent] (global P = 0.042)."
18676988
sparser
"While no single SNP produced significant evidence for association in the Finnish case–control sample, SNP × SNP epistasis analysis of the 66 SNPs selected for replication detected a significant interaction between KCNB2 SNP rs1431656 on chromosome 8q13.3 and CACNB2 SNP rs7076100 on chromosome 10p12.33 (point-wise P = 0.0000199; global P = 0.022)."
18676988