IndraLab

Statements


| 1

eidos
"For instance , while loss of Bap1 activates intrinsic apoptosis in several mouse cell types ( hepatocytes , keratinocytes , fibroblasts , and embryonic stem cells ) in an RNF2-dependent fashion , the Bap1 loss enhances proliferation of melanocytes in association with upregulation of lineage-specific oncogenes MITF and BCL2 , independently of RNF2 ( 48 ) ."