IndraLab

Statements

USP12 activates cell cycle. 4 / 4
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"Additionally, only the overexpression of USP12 promoted cell cycle progression (Fig. 3F, G) and inhibited apoptosis (Fig. 3H, I), whereas USP12 did not."
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"Our data also indicated that over-expression of USP12 WT and its deubiquitinase enhanced mutants promoted cell cycle progression."
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"Flow cytometry analysis also showed that USP12 could induce cell cycle arrest at the G2/Mstage."
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"In addition , USP12 promotes cell survival , proliferation , tumorigenesis , and cell cycle progression by upregulating BMI-1 , c-Myc , and cyclin D2 [ 24,25,26,27 ] ."
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