IndraLab

Statements

USP10 leads to the deubiquitination of mutated TP53. 3 / 3
| 3
reach
"USP10 deubiquitinates p53.wt and mutant p53 and reverses MDM2-induced p53 nuclear export and degradation [12] ."
28587923
reach
"However, it is unclear whether USP10 antagonizes ubiquitination of mutp53 by other ubiquitin ligases, USP10 alters subcellular localization of mutp53, and USP10 plays a role in deubiquitination of different TP53 mutants."
30577483
reach
"USP10 deubiquitinates and stabilizes both wt and mutant p53."
26734569