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USP13 deubiquitinates PRPF6. 2 / 2
| 2

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"We subsequently determined that USP13 significantly reduced the polyubiquitination of PRPF6, with a specific focus on the K48 and K63 chain linkages (Figures 5D,E)."

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"The results above indicate that USP13 deubiquitinates PRPF6, thereby stabilising its protein levels and promoting the proliferation of HCC cells via modulation of the AKT‐mTOR signalling pathway."