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USP19 activates TRIM69. 2 / 2

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"Previous studies have demonstrated that USP19 mediates the deubiquination of TAK1 and TRIF, thereby inhibiting TNF-α/IL-1β and TLR3/4 signaling, respectively [14,15]."

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"However, USP13, USP19, and USP22 inhibit virus-induced IFN production by removing K27-linked polyubiquitin chains from STING (40, 81) or TRIF (90)."

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IndraLab

Statements

USP19 activates TRIM69. 2 / 2

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