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Histamine activates KCNK18. 3 / 3
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"Evidence that TRESK is activated by histamine [8] affords speculation that the physiological role of TRESK currents is to ' dampen ' cellular excitability in inflammatory responses.Based on the above [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The authors also discuss the coupling of TRESK to the histamine H1 receptor, mention that histamine can activate TRESK channels, and speculate that the physiological role of TRESK currents is to dampe[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, TRESK is activated by histamine, an important mediator in local immune responses, and its activity is inhibited by addition of pyriamine, an H1 receptor antagonist [40] ."
19852929