IndraLab

Statements



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"These results suggested that knockdown of MYSM1 alleviated DOX-induced cardiotoxicity."

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"MYSM1 alleviates DNA damage and inhibits cellular senescence [11, 13], which is associated with DOX-induced cardiotoxicity [14]."

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"Correspondingly, cardiomyocyte-specific knockdown of MYSM1 by AAV9 protected the heart from DOX-induced cardiotoxicity."

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"Knockdown of MYSM1 significantly alleviated DOX-induced cardiotoxicity, including cardiac dysfunction, myocardial interstitial fibrosis, and cardiomyocyte death."