IndraLab

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PRNP binds KCNK2. 4 / 4
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"To test the interaction between PrP C and TREK-1, we employed co-immunoprecipitation assays of transiently over-expressed tagged-proteins in HeLa cells."
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"In order to investigate if the interaction between PrP C and TREK-1 could be further sustained by co-localization in living cells, we produced fluorescent fusion proteins of the two interacting candid[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The PrP C –TREK-1 interaction was also visualized in living eukaryotic cells through a confocal microscopy analysis, employing fluorescent fusion proteins."
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"In conclusion, we have described a novel interaction between the cellular prion protein and the potassium channel TREK-1."
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