IndraLab

Statements


| 8

reach
"CsA, which was added to HPTC simultaneously with the engagement of both CD3 and CD28 or the 1-h-delayed engagement of CD28 after prior TCR and CD3 triggering, inhibited NF-kappaB p65 and RelA from binding to the target DNA fragment, followed by reduction of HPTC proliferation in response to the costimulation."

reach
"To exam whether cyclosporine A (CsA) and a non immunosuppressive analog, sanglifehrin A (Sfa), could also suppress p65 and Rel A, we treated MEF with CsA (1.0 microM) and Sfa (100 nM) to inhibit CypA isomerase activity, followed by examining p65 and RelA expression levels in cytoplasmic and nuclear extracts."

reach
"To exam whether cyclosporine A (CsA) and a non immunosuppressive analog, sanglifehrin A (Sfa), could also suppress p65 and Rel A, we treated MEF with CsA (1.0 microM) and Sfa (100 nM) to inhibit CypA isomerase activity, followed by examining p65 and RelA expression levels in cytoplasmic and nuclear extracts."

reach
"Kinase inhibitors decreased nuclear p65 and DNA binding, in cells treated with CsA."

reach
"The phosphorylated forms of IKKgamma and NF-kappaB p65 were significantly reduced only in the low-salt fed rats treated with CsA, indicating greater NF-kappaB activation under these conditions (XREF_FIG)."

reach
"CsA, which was added to HPTC simultaneously with the engagement of both CD3 and CD28 or the 1-h-delayed engagement of CD28 after prior TCR and CD3 triggering, inhibited NF-kappaB p65 and RelA from binding to the target DNA fragment, followed by reduction of HPTC proliferation in response to the costimulation."

reach
"We used anti-CD3 (OKT3) and anti-CD28 (28.2 or Leu28) for HPTC costimulation and found a rapid change of CsA sensitivity within 30 min after the costimulation.In summary, CsA that was added simultaneo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"We used anti-CD3 (OKT3) and anti-CD28 (28.2 or Leu28) for HPTC costimulation and found a rapid change of CsA sensitivity within 30 min after the costimulation.In summary, CsA that was added simultaneo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"