
IndraLab
Statements
Cyclosporin A inhibits RELA. 8 / 8
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8
reach
"CsA, which was added to HPTC simultaneously with the engagement of both CD3 and CD28 or the 1-h-delayed engagement of CD28 after prior TCR and CD3 triggering, inhibited NF-kappaB p65 and RelA from binding to the target DNA fragment, followed by reduction of HPTC proliferation in response to the costimulation."
reach
"To exam whether cyclosporine A (CsA) and a non immunosuppressive analog, sanglifehrin A (Sfa), could also suppress p65 and Rel A, we treated MEF with CsA (1.0 microM) and Sfa (100 nM) to inhibit CypA isomerase activity, followed by examining p65 and RelA expression levels in cytoplasmic and nuclear extracts."
reach
"To exam whether cyclosporine A (CsA) and a non immunosuppressive analog, sanglifehrin A (Sfa), could also suppress p65 and Rel A, we treated MEF with CsA (1.0 microM) and Sfa (100 nM) to inhibit CypA isomerase activity, followed by examining p65 and RelA expression levels in cytoplasmic and nuclear extracts."
reach
"CsA, which was added to HPTC simultaneously with the engagement of both CD3 and CD28 or the 1-h-delayed engagement of CD28 after prior TCR and CD3 triggering, inhibited NF-kappaB p65 and RelA from binding to the target DNA fragment, followed by reduction of HPTC proliferation in response to the costimulation."