IndraLab

Statements


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"We used anti-CD3 (OKT3) and anti-CD28 (28.2 or Leu28) for HPTC costimulation and found a rapid change of CsA sensitivity within 30 min after the costimulation.In summary, CsA that was added simultaneo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"To exam whether cyclosporine A (CsA) and a non immunosuppressive analog, sanglifehrin A (Sfa), could also suppress p65 and Rel A, we treated MEF with CsA (1.0 microM) and Sfa (100 nM) to inhibit CypA isomerase activity, followed by examining p65 and RelA expression levels in cytoplasmic and nuclear extracts."

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"To exam whether cyclosporine A (CsA) and a non immunosuppressive analog, sanglifehrin A (Sfa), could also suppress p65 and Rel A, we treated MEF with CsA (1.0 microM) and Sfa (100 nM) to inhibit CypA isomerase activity, followed by examining p65 and RelA expression levels in cytoplasmic and nuclear extracts."

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"The phosphorylated forms of IKKgamma and NF-kappaB p65 were significantly reduced only in the low-salt fed rats treated with CsA, indicating greater NF-kappaB activation under these conditions (XREF_FIG)."

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"Kinase inhibitors decreased nuclear p65 and DNA binding, in cells treated with CsA."

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"We used anti-CD3 (OKT3) and anti-CD28 (28.2 or Leu28) for HPTC costimulation and found a rapid change of CsA sensitivity within 30 min after the costimulation.In summary, CsA that was added simultaneo[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"