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Aldehyde binds OTUB1. 5 / 5
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"Recently, the protein encoded by FLJ20113 was named otubain 1 (OTU-domain ubiquitin aldehyde-binding protein) as a member of a family of cysteine proteases involved in ubiquitin signaling capable of c[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"This occurred through the stabilization of ubiquitin aldehyde binding 1 (OTUB1) mRNA in a plakophilin 3 (PKP3)-dependent manner, with METTL3 mediating the m6A modification and circularization of circIGF2BP3 in a YTHDC1-dependent manner [119]."
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"Another study revealed that circIGF2BP3 functioned as the molecular sponge of miR-328-3p and miR-3173-5p to upregulate plakophilin 3 (PKP3) expression, thereby increasing ovarian tumor (OTU) family deubiquitinase ubiquitin aldehyde binding 1 (OTUB1) level and facilitating PD-L1 deubiquitination [8]."
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"Knockdown of lncRNA GAS6-AS2 impedes the miR-493-5p/OTU domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) axis, which inhibits the phosphorylation levels of PI3K, AKT and forkhead box cla[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Drug affinity responsive target stability (DARTS), cellular thermal migration assay (CETSA), molecular docking, and Surface plasmon resonance (SPR) assay were used to confirm Erianin binding to ovarian tumor ubiquitin aldehyde-binding protein 1 (OTUB1) protein."
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