IndraLab

Statements

USP25 activates FOXP3. 4 / 4
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"Here USP21 prevents FOXP3 degradation most likely through removing K48 linked polyubiquitin moieties."
27857073
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"USP21 prevents the loss of FOXP3 protein in Treg cells."
27857073
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"Therefore, USP21 prevents the proteasomal degradation of FOXP3 in Treg cells."
27857073
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"Interestingly, Foxp3 directly activates expression of USP21, and siRNA knockdown of USP21 downregulates both GATA3 and Foxp3 protein."
26085205