IndraLab

Statements


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sparser
"It has been shown in vitro that uPAR crucially influences integrin function ( xref ): the presence of uPAR inhibited β 1 integrin– mediated cell binding to fibronectin, whereas uPAR favored β 2 integrin–dependent monocyte adhesion to fibrinogen, one of the adhesive ligands of Mac-1."

sparser
"Mechanistic studies have shown that overexpression of uPAR in tumor cells confers enhanced proliferative, inva-sive, and metastatic potential through the interaction of uPAR with integrins and fibronectin [ xref , xref , xref , xref , xref ]."