IndraLab

Statements

TP53 binds APP, PSEN1, APP, and IAPP. 1 / 1

| 1

sparser

"A recently published model states that p53 transcription is upregulated by the formation of the amyloid intracellular domain (AICD) during presenilin-dependent γ-secretase cleavage of APP with increased p53 subsequently activating PrP C transcription [ xref ]."

21619641

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

TP53 binds APP, PSEN1, APP, and IAPP. 1 / 1

INDRA sources:

Databases

Reading