IndraLab

Statements

TNF binds INSR. 11 / 11
| 1 10
sparser
"The HIRMAb-TNFR fusion protein binds both the HIR and TNFα with low nM affinity."
21327054
sparser
"Actual and potential interactions between cell receptor signaling pathways (receptor cross-talk): interaction between TNF-α and the insulin receptor."
12110133
sparser
"On day 11, M1 and M2 activation was observed in both groups, whereas IL-10-IR M2 levels were attenuated in SAMP8 mice, and the number of TNF-α-IR M1 cells increased, compared to those in SAMR1 mice."
33114176
sparser
"In the TNF-IR group, the RRs of the ASAS20, ASAS40, and ASAS5/6 were 1.44 (95% CI = 1.04 to 1.99, P = 0.03), 2.22 (95% CI = 0.66 to 7.41, P = 0.20), and 4.86 (95% CI = 0.53 to 44.93, P = 0.16), respectively, and the magnitudes of improvements in the ASAS40 and ASAS5/6 were statistically nonsignificant ( xref )."
33192173
sparser
"One scenario could be a direct interaction of TNF -α affecting the insulin receptor [ xref , xref , xref , xref ]."
31940889
sparser
"These results suggested that secukinumab 150 mg provided benefits for TNFi-naive and TNF-IR patients."
33192173
reach
"Actual and potential interactions between cell receptor signaling pathways (receptor cross-talk) : interaction between TNF-alpha and the insulin receptor."
12110133
sparser
"In the TNF-IR group, there was a trend that secukinumab 150 mg provided higher ASAS40 and ASAS5/6 response rates, although the magnitudes of the improvements were statistically nonsignificant."
33192173
sparser
"For instance, in the trials including TNF-IR patients, 9 patients from Asia were involved compared with 133 patients from the USA."
32182362
sparser
"M1 levels and the number of TNF-α-IR M1 were increased on day 3 in SAMP8 mice compared with those in SAMR1 mice."
33114176
sparser
"Donnahoo et al. [9] have shown that I–R-induced renal TNF production was associated with impaired renal function and TNF-binding protein restored creatinine clearance."
14675562