IndraLab

Statements


OTUB2 inhibits RIPK3. 2 / 2
| 2

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"Mechanistically, OTUB2 inhibited the degradation of RIPK3 through removing K48-linked polyubiquitin chains from RIPK3, thereby enhancing RIPK3 abundance and activation."

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"Moreover, OTUB2 increased RIPK3 protein abundance by inhibiting the proteasomal degradation of RIPK3."