IndraLab

Statements


MiRP1 COOH terminus activates KCNQ1. 2 / 2
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"The converse chimera consisting of the MiRP1 COOH terminus in a MinK background does modulate KvLQT1, suggesting that the MiRP1 COOH terminus can modulate KvLQT1 gating in concert with the MinK transmembrane domain."

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"Furthermore, using chimeric analysis between two members of the KCNE family, we show that the MiRP1 COOH terminus can modulate KvLQT1 in the presence of the MinK transmembrane domain."