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KCNQ1 activates localization. 2 / 2
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"The LQT1-related T587M mutation in KCNQ1 for example does not only reduce I , but also fails to increase membrane localization of the KCNH2-encoded K 11.1 protein, as opposed to wild-type KCNQ1, thus also reducing I (61)."
30123799
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"However, I Kr was substantially reduced by KCNQ1-T587M transfection, suggesting that the effect of endogenous KCNQ1 to enhance KCNH2 membrane localization is overcome by overexpressed KCNQ1-T587M, pos[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
19959132