IndraLab

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USP19 decreases the amount of TP53. 2 / 2
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"We also demonstrate that CRISPR/Cas9-mediated knockout of USP19 in cervical cancer cells elevates p53 protein levels, resulting in reduced colony formation, cell migration, and cell invasion."

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"Overall, our results indicate that USP19 negatively regulates p53 protein levels in cervical cancer progression."