IndraLab

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UCHL3 inhibits CUL1. 4 / 4
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"We reveal that UCHL3 can inhibit Cullin1 neddylation in cells dependently on COPS5."
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"We found that overexpression of increased amounts of UCHL3 gradually inhibited endogenous Cullin1 neddylation, indicating that cellular Cullin1 neddylation are regulated by UCHL3 levels."
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"Our results showed that UCHL3 overexpression inhibits Cullin1 neddylation."
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"We find that in cells UCHL3 can decrease neddylation of Cullin1."
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