IndraLab

Statements

TNFAIP3 inhibits TLR3. 3 / 3
| 1 2
sparser
"A20 can inhibit TLR3 signals and can bind TRAF6, Nef-associated kinase/TANK-binding kinase 1, and IκB kinase ε ( xref – xref )."
18268035
sparser
"In addition to activating NF-κB, A20 efficiently inhibits TLR3- and RIG-I-mediated signaling to IRF-3 and NF-κB transcription factors [83–85] ."
18707898
eidos
"41 In addition , A20 interacts with TRIF and inhibits TLR3 - and Sendai virus-induced activation of IFN-sensitive response element and IFN-beta promoter , suggesting that A20 is a virus-inducible protein that blocks both inflammatory and cellular antiviral responses ."
23909285