IndraLab

Statements

ATXN3 inhibits TP53BP1. 2 / 2
| 2
reach
"Consistent with defective DSB induced ubiquitylation, we found that depletion of ataxin-3 also significantly reduced both BRCA1 (Fig XREF_FIG D) and 53BP1 accumulation (Fig XREF_FIG E) to laser inflicted DNA damage, as well as to ionizing radiation induced foci (XREF_SUPPLEMENTARY and XREF_SUPPLEMENTARY)."
28275011
reach
"Indeed, we found that over-expression of ataxin-3 in control cells already significantly reduced accrual of 53BP1 (XREF_SUPPLEMENTARY)."
28275011