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"The gametes of different mating types allogenically recognize each other through the interaction of SAD1 and SAG1 and initiate the gamete activation processes, making their apical tips accessible by i[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"The interaction is strong and may indeed be irreversible, since the Sag1-Sad1 complex is proteolytically shed into the medium [23] ."