IndraLab

Statements

USP2 binds epithelial sodium channel. 3 / 3
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"The interaction of Usp2-45 with ENaC exogenously expressed in HEK293 cells was tested by coimmunoprecipitation."
21478478
sparser
"Here, in HEK293 cells stably transfected with ENaC, Usp2-45 interacted with ENaC, leading to deubiquitylation of the channel and stimulation of ENaC activity >20-fold."
18701608
sparser
"They report that Usp2-45 interacts directly with ENaC, although not with the PY-motif, to alter both cell surface expression and furin, but not prostasin, cleavage."
18269346