IndraLab

Statements

Dioscin inhibits NLRP3. 5 / 5
| 5
reach
"Western blotting results suggested that dioscin inhibited the activation of NLRP3 through down-regulating the protein expressions of NLRP3, apoptosis associated speck like protein containing a caspase recruitment domain (ASC), cleaved-caspase-1, as well as IL-1beta."
32761488
reach
"In vitro experiments, the results showed that dioscin inhibited the inflammatory response and the activation of NLRP3 inflammasome, but the survival rate of mouse mammary epithelial cells (mMECs) induced by LPS+ATP is increased."
33488936
reach
"Meanwhile, dioscin dramatically suppressed NLRP3 inflammasome activation."
33904167
reach
"Moreover, dioscin also can reduce the production of proinflammatory factors such as interleukin-1 beta (IL-1beta) and inhibit the activation of NLRP3 inflammasome in LPS induced mice mastitis."
33488936
reach
"Dioscin Reduces LPS+ATP-Induced Activation of NF-kappaB Signaling Pathway and NLRP3 Inflammasome in mMECs."
33488936