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OTUD5 decreases the amount of IL17A. 1 / 1

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"Accumulation of the deubiquitinating enzyme DUBA (OTUD5) negatively regulates RORgammat stability and IL-17 expression in T cells by stabilizing the ubiquitin ligase UBR5, which ubiquitinates RORgammat in response to TGF-beta, leading to RORgammat degradation and decreased IL-17 expression."

31386594

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IndraLab

Statements

OTUD5 decreases the amount of IL17A. 1 / 1

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