IndraLab

Statements

FN1 binds ITGAV and ITGB3. 2 / 2
1 1 |
bel
"binding to these ligands by alphaVbeta3 allows endothelial cells to migrate into the adjacent stroma, and blocking alphaVbeta3 not only prevents endothelial cell migration and angiogenesis but also leads to apoptosis of endothelial cells"
12793895
bel
"The integrin-RTK cooperation may make it possible for cell attachment to induce an RTK response independently of the growth factor ligand. Cells that attach to fibronectin (a ligand of avb3) show autophosphorylation of PDGF-Rb (6) and relocation of the receptor to focal contacts"
10964931