IndraLab

Statements


KCNB1 activates FYN. 3 / 3
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"Pharmacological inhibition of integrin signaling or FAK suppressed apoptosis induced by oxidation of KCNB1, as well as FAK and Src and Fyn activation."

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"Together these data led us to conclude that KCNB1 oligomers activate an integrin-FAK-Src and Fyn apoptotic pathway that is conserved in both primary hippocampal neurons and mammalian cells."

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"Pharmacological inhibition of integrin signaling or FAK suppressed apoptosis induced by oxidation of KCNB1, as well as FAK and Src and Fyn activation."