IndraLab

Statements


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"Hence, we hypothesize that the OTUD5-MAVS complex may exert a pivotal regulatory influence in the progression of PBC disease, exhibiting tissue-specific significance."

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"High expression of OTUD5-MAVS in Subpopulation 11 of mononuclear macrophages was screened by PBMC ScRNA-seq."

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"This study also revealed a specific monocyte subset with OTUD5MAVS interaction in PBC by single-cell sequencing."

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"High expression of OTUD5-MAVS in subpopulation 11 mononuclear macrophages was screened by PBMC scRNA-seq, and mononuclear cells with the subgroup 11 phenotype presented highly differentiated characteristics."

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"Proteomic and immunofluorescence analyses revealed that the interaction between OTUD5 and MAVS could regulate the immunopathology of PBC."

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"Potential interactions between OTUD5 and MAVS are suggested in proteomic predictions, offering intriguing insights into their potential interplay."

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"This study revealed a potential interaction between OTUD5 and MAVS."

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"This comprehensive analysis revealed the presence of OTUD5-MAVS molecular markers in monocytes, along with significant variations in macrophage profiles in the peripheral blood of patients with PBC."