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USP29 activates epithelial to mesenchymal transition. 3 / 3
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"And the simultaneous depletion of TWIST1 largely reversed such an effect induced by USP29 overexpression (Figure S3A,B, Supporting Information), indicating the driven EMT process by USP29 is mediated by TWIST1."
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"19 In addition, the transcription of USP29 in gastric cancer cells could also be induced by TGF‐β, TNFα, and hypoxia, which were reported to be present in the tumor microenvironment and promote EMT and metastasis."
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"For example, USP3, USP11, and USP29 stimulate EMT in glioblastoma cells, as well as in ovarian or gastric cancer cells, respectively, by stabilizing Snail [80–82] ."
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