IndraLab

Statements

TRPA1 binds IL1B. 3 / 3
| 3
sparser
"While the rapid response suggests a potential direct interaction between IL-1β and TRPA1 channel subunits, indirect activation via adjacent membrane components cannot be excluded."
40143111
sparser
"In addition to the mechanisms described above, a more direct interaction between TRPA1 and IL-1β in MSU crystal-induced inflammation is possible, as TRPA1 activation has been reported to enhance IL-1β production in keratinocytes [ xref ], and a similar effect was found in the present study in the air-pouch model."
25658427
sparser
"From understanding mechanisms of vagus TRPA1 nociceptors and IL-1β in stimulating reflex anti-inflammatory responses may come novel therapeutic insights based on IL-1β-TRPA1 vagus nociceptor signaling."
36650454