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"Likewise, studies with cortical cultures from Usp14 axJ mice [XREF_BIBR] which exhibit a 90-95% loss of USP14 (XREF_FIG, panel 1), show that USP14 depletion failed to prevent the deleterious effects of PGJ2 tested, i.e. caspase activation and accumulation of Ub-proteins (XREF_FIG, panels 2 and 3, respectively)."