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USP7 deubiquitinates RELA. 2 / 3

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"However, USP7 deubiquitinates the NF-kappaB p65 subunit, which is an important regulator of inflammation, but the USP7 inhibitor targets all the substrates of USP7, not only p65."

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"Deubiquitination of p65 by USP7, 15, and 48 can stabilize p65 and upregulate the NF-κB activity (Table 2) (56-58)."

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USP7 deubiquitinates RELA. 2 / 3

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