IndraLab

Statements


OTUD5 activates IFNB1. 2 / 2
| 2

reach
"DUBA knockdown by siRNA transfection in Il1r1 -/- BMDCs (XREF_FIG) resulted in significantly increased IL-10 and IFN-beta production and decreased secretion of IL-6, but not TNF, in CpG stimulated Il1r1 -/- BMDCs (XREF_FIG)."

reach
"The removal of endogenous DUBA by siRNA produced an elevated IFN-β and IFN-α response to poly:IC or Sendai virus, whereas NF-κB activation was predominantly unaffected ( Kayagaki et al., 2007 )."