IndraLab
Statements
"In addition, <span class="match term0">USP9X</span> can also function as a tumor suppressor. <span class="match term0">USP9X</span> strongly interacts with LATS, a core kinase in the Hippo pathway. Increased <span class="match term0">USP9X</span> expression significantly up-regulates and stabilizes LATS and leads to a decrease in the transport of YAP/TAZ into the nucleus as well as inhibiting of their target genes."