IndraLab

Statements

USP18 binds MYC. 4 / 4
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"Immunofluorescence assay showed that Myc-USP18 exhibited colocalization with Flag-MAVS (Fig.  xref )."
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"Because of its deubiquitinase activity, USP18 interacts with Myc to catalyse the deubiquitination of Nothc1, thereby enhancing the Notch1- c -Myc axis and promoting the progression of pancreatic cance[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"There were no red spots when Myc-USP18 was co-transfected with the control Flag vector, while the transfection of both Myc-USP18 and Flag-MAVS resulted in significant numbers of red spots (Fig.  xref )."
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"To further clarify the mechanism through which USP18 regulates c-Myc in pancreatic cancer cells, we first determined whether there was a direct interaction between the USP18 and c-Myc proteins."
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