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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP14 inhibits IKB. 3 / 3

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"This finding is consistent with another study demonstrating that the inhibition of USP14 increases IkappaB stability in rat lungs and prevents ventilator induced lung injury."

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"In microbial infection , USP14 induced IkappaB degradation and promoted lipopolysaccharide ( LPS ) - mediated activation of NF-kappaB19 ."

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"We previously showed that USP14 decreases the stability of IkappaB by interacting with the NF-kappaB subunit RelA."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...