IndraLab

Statements

USP49 activates SIRT1. 2 / 2
| 2
reach
"Furthermore, it was also revealed that IGF2BP3‐dependent m6A modification of USP49 enhances autophagy by stabilizing SIRT1 via its deubiquitination, helping RB cells survive under CBP treatment."
39497328
reach
"Our findings revealed that IGF2BP3‐dependent m A modification of USP49 mRNA upregulates USP49 expression to enhance SIRT1 stability.These findings highlight the critical role of USP49 in cellular processes and its potential as a therapeutic target in RB."
39497328