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USP7 bound to TRIM27 inhibits IFNB1. 1 / 1

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"In SeV infection there seems to be another mechanism at work; the ubiquitin-specific peptidase 7 (USP7) interacts with and stabilizes TRIM27, promoting the degradation of TBK1 and suppressing the activation of IFN-β (Cai et al., 2018)."

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USP7 bound to TRIM27 inhibits IFNB1. 1 / 1

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