IndraLab

Statements

USP19 inhibits TNF. 3 / 3
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sparser
"For example, USP19 inhibits Tnf and Il1b-triggered NF-κB activation by targeting TAK1 uncoupling of k27 and k63-linked polyubiquitin chains ( xref )."
37304282
reach
"USP19 attenuates the TNF-α– and IL-1β–triggered inflammatory response via deubiquitination of TGF-β-activated kinase 1."
38716888
sparser
"Removal of K27- and K63-linked chains by USP19 inhibited TNFα- and IL-1β-induced NFκB activation, suggesting that these ubiquitin chains normally activate TAK1 downstream signaling ( xref )."
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