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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP18 increases the amount of BBC3. 1 / 1

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"USP18 depletion significantly upregulated DP5 and PUMA expression after IFNalpha treatment, and this effect was totally reversed by double knockdown of USP18 and STAT1 (XREF_FIG and g) or STAT2 (XREF_FIG and h), suggesting that IFNalpha induced DP5 and PUMA upregulation in USP18 inhibited cells is controlled by STAT1 and STAT2."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...