IndraLab
Statements
Doxorubicin inhibits NLRP3. 6 / 6
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6
reach
"DHM can also inhibit doxorubicin-induced activation of the NLR family pyrin domain-containing 3 (NLRP3) inflammasome in H9C2 cells by blocking cysteinyl-aspartate-specific proteinase-1 (caspase-1) activity, suppressing IL-1β and IL-18 release, and upregulating sirtuin 1 (SIRT1) protein levels in vivo and in vitro [21]."