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USP3 leads to the ubiquitination of CLSPN. 1 / 1

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"Moreover, increased USP3 transcriptionally modulated by Smoothened (Smo) reduces Claspin polyubiquitination and proteasomal degradation, leading to activation of Claspin-dependent ATR-CHK1 signaling and radiation resistance of glioblastoma (GBM) [115]."

36694209

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IndraLab

Statements

USP3 leads to the ubiquitination of CLSPN. 1 / 1

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