IndraLab

Statements

USP8 is phosphorylated on Y810. 5 / 5
| 5
rlimsp
"EGFR activates USP8 by phosphorylating Tyr-717 and Tyr-810."
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rlimsp
"In contrast, Kasahara et al. [88] reported that EGFR kinase suppresses ciliogenesis by phosphorylating USP8 on Tyr717 and Tyr810 enhancing the deubiquitinase activity."
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rlimsp
"USP8 is activated by EGFR-mediated phosphorylation at Tyr-717 and Tyr-810, and this phosphorylation is essential for suppressing ciliogenesis (Figs. 7 and 8)."
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rlimsp
"In vitro phosphorylation assays identified Tyr-717 and Tyr-810 as the major phosphorylation sites of USP8 (Supplementary Fig. 11)."
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rlimsp
"In this study, we show that EGFR activation is responsible for this process by directly phosphorylating USP8 on Tyr-717 and Tyr-810."
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