IndraLab

Statements

BAP1 activates XRCC1. 4 / 4
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"Meta-analyses have indicated that mutations in PBRM1 and SETD2 tend to occur together, but mutations in PBRM1 and BAP1 tend to be mutually exclusive and are thought to underlie different pathologic fe[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"While BAP1 deletion suppresses RCC cell survival in vitro, it does not impede tumor growth in immunocompetent murine models."
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"BAP1 syndrome increases the risk of aggressive RCC, cutaneous melanocytic lesions, basal cell carcinoma, mesothelioma (frequently in the abdomen) and uveal melanoma [151,152,153]."
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"BAP1 syndrome increases the risk of aggressive RCC, cutaneous melanocytic lesions, basal cell carcinoma, mesothelioma (often in the abdomen), and uveal melanoma [97]."
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