IndraLab

Statements

FKBP8 activates KCNH2. 4 / 4
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"FKBP8 is reported to promote the maturation of HERG channel and cystic fibrosis transmembrane conductance regulator (CFTR) XREF_BIBR, XREF_BIBR."
29129702
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"Additionally, siRNA knock-down of FKBP38 causes a reduction in HERG trafficking and overexpression of wild type FKBP38 partially rescues HERG trafficking in the presence of F805C disease causing KCNH2 mutation XREF_BIBR."
20975010
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"Overexpression of FKBP38 was also able to partially rescue a hERG trafficking mutant, F805C."
20670193
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"Co-chaperone FKBP38 promotes HERG trafficking."
17569659