IndraLab

Statements

Inositol inhibits CASP1. 4 / 4
| 4
reach
"Here, a model integrates both biochemical and cellular data to provide a more quantitative estimation of MI inhibition of CA/SP1 cleavage, and thus formation of mature viruses in vivo."
27893830
reach
"To complete the data required to model MI inhibition of CA/SP1 cleavage (XREF_FIG) as a function of MI and Gag polymorph, specific binding affinities of BVM, BMS-1 and BMS-955176 toward VLPs containing Gag polymorphs were determined through the use of a competitive radioligand binding assay (XREF_TABLE)."
27893830
reach
"Since it has been also documented that acute MI increased caspase-1 activity and formation of inflammasome [XREF_BIBR], decreased miR-1 during MI might be an unappreciated propyroptosis mechanism by which the synthesis of inflammasome components is enhanced contributing to the development of pyroptosis."
26491223
reach
"In seeking the mechanistic origins of this behavior we initially considered a simplified model for MI inhibition of CA/SP1 cleavage of viral particles in which cleavage only takes place in that fraction of particles not bound to the MI."
27893830